Absence of mutations associated with resistance to benzimidazole in the beta-tubulin gene of Ascaris suum
Rev. Soc. Bras. Med. Trop
;
53: e20190155, 2020. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1092219
ABSTRACT
Abstract INTRODUCTION:
Benzimidazoles are commonly used for the control of veterinary nematodes. Resistance to benzimidazoles has been associated with three single nucleotide polymorphisms in the β-tubulin gene of common nematodes. However, these mutations are infrequent in the genus Ascaris spp.METHODS:
In order to determine mutations associated with benzimidazole resistance in Ascaris suum, worms were collected from slaughtered pigs and a partial region of the β-tubulin gene was sequenced.RESULTS:
All parasites showed the wildtype genotype for codons 167, 198, and 200 of the β-tubulin gene.CONCLUSIONS:
This is the first report of genetic sequences associated with benzimidazole resistance in A. suum.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Benzimidazóis
/
Resistência a Medicamentos
/
Ascaris suum
/
Mutação
Tipo de estudo:
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Canadá
/
Honduras
Instituição/País de afiliação:
Brock University/CA
/
Universidad Nacional Autónoma de Honduras (UNAH)/HN
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