Adherence to antiretroviral therapy among people living with HIV/AIDS in northeastern Brazil: a cross-sectional study
São Paulo med. j
;
137(6): 479-485, Nov.-Dec. 2019. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1094528
ABSTRACT
ABSTRACT BACKGROUND:
Nonadherence to antiretroviral therapy (ART) may lead to viral replication and development of antiretroviral resistance.OBJECTIVE:
To identify the factors associated with nonadherence to ART among people living with the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) (PLWHA). DESIGN ANDSETTING:
Cross-sectional study in a tertiary-level hospital in northeastern Brazil.METHODS:
Intake of less than 90% of the antiretroviral drugs prescribed in the last week prior to the interview was defined as nonadherence. Intake was evaluated using a questionnaire. Descriptive and multivariate analyses were conducted on the study population, with estimation of the respective odds ratios and 95% confidence intervals.RESULTS:
The prevalence of nonadherence was 28.4%. Significant associations were found regarding the following variables age less than 35 years, smoking, sedentary lifestyle, lack of medication and lack of knowledge regarding the patient's HIV status, on the part of the patient's partner or family.CONCLUSIONS:
Encouragement of adherence to antiretroviral therapy is one of the fundamental pillars of treatment for HIV-infected patients. The high proportion of nonadherence (28.4%) and the predictive factors related to this indicate that it is necessary to improve patients' adherence to antiretroviral therapy.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções por HIV
/
Fármacos Anti-HIV
/
Terapia Antirretroviral de Alta Atividade
/
Adesão à Medicação
/
Cooperação e Adesão ao Tratamento
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fundação Oswaldo Cruz/BR
/
Universidade Federal de Pernambuco/BR
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