Panic disorder respiratory subtype: psychopathology and challenge tests - an update
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
42(4): 420-430, July-Aug. 2020. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1132104
ABSTRACT
Panic disorder (PD) pathophysiology is very heterogeneous, and the discrimination of distinct subtypes could be very useful. A subtype based on respiratory symptoms is known to constitute a specific subgroup. However, evidence to support the respiratory subtype (RS) as a distinct subgroup of PD with a well-defined phenotype remains controversial. Studies have focused on characterization of the RS based on symptoms and response to CO2. In this line, we described clinical and biological aspects focused on symptomatology and CO2 challenge tests in PD RS. The main symptoms that characterize RS are dyspnea (shortness of breath) and a choking sensation. Moreover, patients with the RS tended to be more responsive to CO2 challenge tests, which triggered more panic attacks in this subgroup. Future studies should focus on discriminating respiratory-related clusters and exploring psychophysiological and neuroimaging outcomes in order to provide robust evidence to confirm RS as a distinct subtype of PD.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Dióxido de Carbono
/
Transtorno de Pânico
/
Ventilação Pulmonar
/
Hiperventilação
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Instituto de Biofísica Carlos Chagas Filho, UFRJ/BR
/
Instituto de Psiquiatria (IPUB), Universidade Federal do Rio de Janeiro (UFRJ)/BR
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