Health-related quality of life in patients treated with atypical antipsychotics
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
42(6): 599-607, Nov.-Dec. 2020. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1132149
ABSTRACT
Objective:
To assess health-related quality of life and associated factors in patients treated with atypical antipsychotics, as well as to determine utility values using the EuroQol-5D-3L instrument.Methods:
A cross-sectional study was conducted at a state-run pharmacy in the Brazilian National Health System. Individuals were included if they were using a single atypical antipsychotic and completed the EuroQol-5D-3L. Sociodemographic, behavioral, and clinical data were collected. The dependent variable was the EuroQol-5D-3L utility score. Associations between the independent variables and the dependent variable were analyzed in a multiple linear regression model.Results:
A total of 394 patients were included, and their mean utility score was 0.664±0.232. Patients treated with clozapine had the highest mean score (0.762 [0.202]), followed by olanzapine (0.687 [0.230]), risperidone (0.630 [0.252]), ziprasidone (0.622 [0.234]), and quetiapine (0.620 [0.243]). The following variables were related to higher utility scores income, employment, clozapine use, no illicit psychoactive substance use, no suicide attempts, and no comorbidities.Conclusion:
Evaluating health-related quality of life differences in the available atypical antipsychotics can facilitate the choice of treatment, improve health outcomes, and ensure rational prescriptions.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Esquizofrenia
/
Antipsicóticos
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Canadá
Instituição/País de afiliação:
UFMG/BR
/
Universidade Federal de Minas Gerais (UFMG)/BR
/
University of Toronto/CA
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