Heart failure with preserved ejection fraction: an update on pathophysiology, diagnosis, treatment, and prognosis
Braz. j. med. biol. res
;
53(7): e9646, 2020. graf
Artigo
em Inglês
| LILACS, ColecionaSUS
| ID: biblio-1132528
ABSTRACT
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome in which patients have symptoms and signs of HF with normal or near-normal left ventricular ejection fraction (LVEF ≥50%). Roughly half of all patients with HF worldwide have an LVEF ≥50% and nearly half have an LVEF <50%. Thanks to the increased scientific attention about the condition and improved characterization and diagnostic tools, the incidence of HF with reduced ejection fraction (HFrEF) dropped while that of HFpEF has increased by 45%. HFpEF has no single guideline for diagnosis or treatment, the patient population is heterogeneously and inconsistently described, and longitudinal studies are lacking. To better understand and overcome the disease, in this review, we updated the latest knowledge of HFpEF pathophysiology, introduced the existing promising diagnostic methods and treatments, and summarized its prognosis by reviewing the most recent cohort studies.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Volume Sistólico
/
Função Ventricular Esquerda
/
Insuficiência Cardíaca
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Berlin Institute of Health Center for Regenerative Therapies & Berlin - Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum (CVK)/DE
/
Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health/DE
/
Henan Provincial Peoples Hospital/CN
/
Second Affiliated Hospital of Zhengzhou University/CN
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