Genomic surveillance of the Chikungunya Virus (CHIKV) in Northeast Brazil after the first outbreak in 2014
Rev. Soc. Bras. Med. Trop
;
53: e20190583, 2020. tab, graf
Artigo
em Inglês
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136797
ABSTRACT
Abstract INTRODUCTION:
We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak.METHODS:
Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018.RESULTS:
Of the 605 samples, 167 were CHIKV-positive. Viral isolation was achieved for 20 samples; their phylogenetic analysis (E2 protein) revealed the presence of ECSA lineage and reinforced the phylogenetic relationship between ECSA and Indian Ocean lineages.CONCLUSIONS:
The genomic surveillance of CHIKV showed that only ECSA lineage circulated in Bahia since the 2014 outbreak.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Vírus Chikungunya
/
Genoma Viral
/
Febre de Chikungunya
Tipo de estudo:
Estudo de rastreamento
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Universidade Federal da Bahia/BR
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