Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
Rev. Soc. Bras. Med. Trop
;
53: e20190526, 2020. tab, graf
Artigo
em Inglês
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136834
ABSTRACT
Abstract INTRODUCTION:
This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates.METHODS:
Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using polymerase chain reaction and plasmid DNA sequencing.RESULTS:
The bla KPC-2 gene was located between ISKpn6 and a resolvase tnpR in the non-Tn4401 element (NTEKPC-IId). It was detected on a plasmid belonging to the IncQ1 group. CONCLUSIONS To our knowledge, this is the first report of the presence of the bla KPC-2 gene in the NTEKPC-IId element carried by plasmid IncQ1 from infections in Brazil.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Beta-Lactamases
/
Infecções por Klebsiella
/
Klebsiella pneumoniae
/
Antibacterianos
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Centro Universitário Tabosa de Almeida/BR
/
Instituto Aggeu Magalhães/BR
/
Universidade Federal de Pernambuco/BR
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