Antibacterial activity of Cinnamomum cassia L. essential oil in a carbapenem- and polymyxin-resistant Klebsiella aerogenes strain
Rev. Soc. Bras. Med. Trop
;
53: e20200032, 2020. tab, graf
Artigo
em Inglês
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136877
ABSTRACT
Abstract INTRODUCTION:
Essential oils can serve as novel sources of antibiotics for multidrug-resistant bacteria.METHODS:
The multidrug-resistance profile of a Klebsiella aerogenes strain was assessed by PCR and sequencing. The antibacterial activity of Cinnamomum cassia essential oil (CCeo) against K. aerogenes was assessed by broth microdilution and time-kill methods.RESULTS:
K. aerogenes showed high antibiotic resistance. The genes bla KPC-2, ampC, bla CTX-M-15, bla OXA-1, and bla TEM were present. CCeo exhibited an inhibitory effect with a minimum inhibitory concentration of 17.57 μg/mL.CONCLUSIONS:
The antibacterial activity of CCeo makes it a potential candidate for treating carbapenem- and polymyxin-resistant K. aerogenes strains.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções por Klebsiella
/
Enterobacter aerogenes
/
Cinnamomum aromaticum
/
Antibacterianos
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Fundação Oswaldo Cruz/BR
/
Universidade Federal da Grande Dourados/BR
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