Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis
Rev. Soc. Bras. Med. Trop
;
53: e20200101, 2020. tab
Artigo
em Inglês
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136903
ABSTRACT
Abstract INTRODUCTION In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability. We sought to evaluate the impact of fractures and orthopedic surgeries in patients with HAM/TSP. METHODS:
We retrieved the medical records of HAM/TSP patients enrolled in our study center's HTLV-1 clinical cohort between 1989-2018. The selection criteria included (1) diagnosis of HTLV-1 infection using two enzyme-linked immunosorbent assays and/or a confirmatory test, (2) clinical diagnosis of HAM/TSP by neurological assessment, and (3) fractures associated with HAM/TSP.RESULTS:
We identified 24 cases of fractures, 70% of which were females. The median age at the time of fracture was 60 years (IQR=24). Six cases reported fractures in patients under 45 years old. Ten patients (42%) had hip/coccyx fractures, seven (29%) were in the lower extremities, and four (17%) in the upper extremities. Half of these patients reported the use of wheelchairs. Five patients who had previously used canes required the use of wheelchairs after the reported fracture. Eight patients underwent corrective orthopedic surgery as a result of the fracture.CONCLUSIONS:
For HAM/TSP patients, fractures are a complication that can exacerbate their severe impairment.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Vírus Linfotrópico T Tipo 1 Humano
/
Infecções por HTLV-I
/
Paraparesia Espástica Tropical
/
Procedimentos Ortopédicos
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Universidad Peruana Cayetano Heredia/PE
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