Reactivation of Chagas disease after autologous hematopoietic stem cell transplantation
Rev. Soc. Bras. Med. Trop
;
54: e20200143, 2021. graf
Artigo
em Inglês
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1143881
ABSTRACT
Abstract Chagas disease (CD) is a protozoan zoonosis caused by Trypanosoma cruzi. Reactivation of CD occurs via drug-induced immunosuppression before and during transplantation. Here, we report the case of a 62-year-old man diagnosed with classic Hodgkin lymphoma who received highly aggressive conditioning chemotherapy before undergoing stem cell transplantation (SCT). The patient tested positive for CD in pre-transplantation evaluation. The patient exhibited persistent fever and elevated C-reactive protein levels before and after SCT, and was treated with antibiotics. Micro-Strout test showed evidence of trypomastigotes and he was treated with benznidazole until tested negative. Post-transplantation seropositive patients should be screened for possible reactivation.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Trypanosoma cruzi
/
Doença de Chagas
/
Transplante de Células-Tronco Hematopoéticas
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
2021
Tipo de documento:
Artigo
Instituição/País de afiliação:
Clínica FOSCAL/CO
/
Universidad Autónoma de Bucaramanga/CO
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