Heparin-coated vs. non-coated cardiopulmonary bypass circuits: comparing immediate results with different target activated clotting time
Rev. bras. cir. cardiovasc
;
35(6): 913-917, Nov.-Dec. 2020. tab
Artigo
em Inglês
| LILACS, SES-SP
| ID: biblio-1144009
ABSTRACT
Abstract Objective:
To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits.Methods:
A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany).Results:
Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion.Conclusion:
Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Heparina
/
Procedimentos Cirúrgicos Cardíacos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. bras. cir. cardiovasc
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital/TR
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