Consensus on the treatment of vitiligo - Brazilian Society of Dermatology
An. bras. dermatol
;
95(supl.1): 70-82, Nov.-Dec. 2020. graf
Artigo
em Inglês
| LILACS
| ID: biblio-1152776
ABSTRACT
Abstract Background:
Vitiligo is a muco-cutaneous, autoimmune, localized, or disseminated disease, which manifests through hypochromic or achromic macules, with loss in quality of life. The prevalence of vitiligo in Brazil was determined to be 0.54%. There is no on-label medication for its treatment. To date, no Brazilian consensus on the treatment of vitiligo had been written.Objectives:
The objective of this group of Brazilian dermatologists with experience in the treatment of this disease was to reach a consensus on the clinical and surgical treatment of vitiligo, based on articles with the best scientific evidence.Methods:
Seven dermatologists were invited, and each was assigned two treatment modalities to review. Each treatment (topical, systemic, and phototherapy) was reviewed by three experts. Two experts reviewed the surgical treatment. Subsequently, the coordinator compiled the different versions and drafted a text about each type of treatment. The new version was returned to all experts, who expressed their opinions and made suggestions for clarity. The final text was written by the coordinator and sent to all participants to prepare the final consensus. Results/Conclusion:
The experts defined the following as standard treatments of vitiligo the use of topical corticosteroids and calcineurin inhibitors for localized and unstable cases; corticosteroid minipulse in progressive generalized vitiligo; narrowband UVB phototherapy for extensive forms of the disease. Surgical modalities should be indicated for segmental and stable generalized vitiligo. Topical and systemic anti-JAK drugs are being tested, with promising results.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Terapia Ultravioleta
/
Vitiligo
/
Dermatologia
Tipo de estudo:
Guia de Prática Clínica
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Hospital de Clínicas de Porto Alegre/BR
/
Pontifícia Universidade Católica do Paraná/BR
/
Private Clinic/BR
/
Santa Casa de Misericórdia de Belo Horizonte/BR
/
Santa Casa de Misericórdia de Curitiba/BR
/
Santa Casa de Misericórdia de São Paulo/BR
/
Universidade do Estado do Rio de Janeiro/BR
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