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The value of preoperative systemic immune-inflammation index in predicting vascular invasion of hepatocellular carcinoma: a meta-analysis
Wu, YiFeng; Tu, ChaoYong; Shao, ChuXiao.
  • Wu, YiFeng; The First Affiliated Hospital of Wenzhou Medical University. Department of Hepatobiliary and Pancreatic Surgery. Wenzhou. CN
  • Tu, ChaoYong; The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital. Department of Hepatobiliary and Pancreatic Surgery. Lishui. CN
  • Shao, ChuXiao; The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital. Department of Hepatobiliary and Pancreatic Surgery. Lishui. CN
Braz. j. med. biol. res ; 54(4): e10273, 2021. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1153542
ABSTRACT
Vascular invasion and systemic immune-inflammation index (SII) are risk factors for the prognosis of patients with hepatocellular carcinoma. At present, the correlation between the two is not clear. This meta-analysis explored the relationship between preoperative SII and vascular invasion in patients with hepatocellular carcinoma. According to the search formula, the Pubmed, Embase, Cochrane, Web of Science, and CNKI databases were searched for the relevant research until March 2020. After the quality evaluation of the included literature, the odds ratio (OR) and its corresponding 95% confidence interval (CI) were used as the effect measure. Stata 15. 0 software was used for statistical analysis. The meta-analysis eventually included seven retrospective cohort studies of 3583 patients with hepatocellular carcinoma. The results showed that the choice of SII cut-off value affects SII's efficiency in predicting the risk of vascular invasion. In the cohort of studies with appropriate SII cut-off value, the high SII preoperative group had a higher risk of vascular invasion (OR=2.62; 95%CI 2.07-3.32; P=0.000) and microvascular invasion (OR=1.82; 95%CI 1.01-3.25; P=0.045) than the low SII group. The tumor diameter (OR=2.88; 95%CI 1.73-4. 80; P=0.000) of the high SII group was larger than that of the low SII group. There was no publication bias in this study (Begg's test, P=0.368). As a routine, cheap, and easily available index, SII can provide a certain reference value for clinicians to evaluate vascular invasion before operation.
Assuntos


Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco / Revisões Sistemáticas Avaliadas Limite: Humanos Idioma: Inglês Revista: Braz. j. med. biol. res Assunto da revista: Biologia / Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital/CN / The First Affiliated Hospital of Wenzhou Medical University/CN

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco / Revisões Sistemáticas Avaliadas Limite: Humanos Idioma: Inglês Revista: Braz. j. med. biol. res Assunto da revista: Biologia / Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital/CN / The First Affiliated Hospital of Wenzhou Medical University/CN