Previous preeclampsia and its association with the future development of cardiovascular diseases: a systematic review and meta-analysis
Clinics
;
76: e1999, 2021. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1153961
ABSTRACT
Preeclampsia is a multifactorial disease. Among these factors, untreated hypertension during pregnancy can result in high morbidity and mortality rates and may also be related to the future development of cardiovascular diseases.Therefore, this systematic review aimed to determine the association of previous preeclampsia with the future development of cardiovascular diseases. Studies on the association between preeclampsia and future cardiovascular diseases published in the last 10 years (2009-2019) were identified from the PubMed/Medline (207 articles), Embase (nine articles), and Cochrane (three articles) databases using the keywords "preeclampsia" and "future cardiovascular diseases", "preeclampsia" and "future heart attack", and "preeclampsia" and "future cardiac disease". After applying the inclusion and exclusion criteria, 15 articles were analyzed by systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The meta-analysis and the determination of the quality of the articles were conducted using RevMan software, version 5.3. Statistically significant differences were observed between the control and previous preeclampsia groups with respect to systolic blood pressure (mean difference [MD] 4.32; 95% confidence interval [95%CI] 3.65, 4.99; p<0.001), diastolic blood pressure (MD) 2.11; 95%CI 1.68, 2.55; p<0.0001), and insulin level (MD 2.80; 95% CI 0.50, 5.11; p<0.001). Body mass index (MD 2.57, 95%CI 2.06, 3.07; p=0.0001), total cholesterol (MD 10.39; 95%CI 8.91, 11.87; p=0.0001), HDL (MD 2.83; 95%CI 2.20, 3.46; p=0.0001), and LDL (MD 1.77; 95%CI 0.42, 3.13; p=0.0001) also differed significantly between groups. Thus, the results of the present study showed that women with a history of preeclampsia were more likely to develop cardiovascular disease.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Pré-Eclâmpsia
/
Doenças Cardiovasculares
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
/
Revisões Sistemáticas Avaliadas
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Clinics
Assunto da revista:
Medicina
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Departamento de Odontologia Pediatrica, Escola de Odontologia de Ribeirao Preto, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo (FMRP-USP)/BR
/
Departamento de Puericultura e Pediatria, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo (FMRP-USP)/BR
/
Hospital Universitario, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo (FMRP-USP)/BR
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