Efficacy of endometrial cancer follow-up protocols: time to change?
Rev. bras. ginecol. obstet
;
43(1): 41-45, Jan. 2021. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1156074
ABSTRACT
Abstract Objective The aim of the present study was to analyze relapse rates and patterns in patients with endometrial cancer with the aim of evaluating the effectiveness of current follow-up procedures in terms of patient survival, as well as the convenience of modifying the surveillance strategy. Methods Retrospective descriptive study including all patients diagnosed with endometrial cancer relapse at the Department of Gynecology and Obstetrics of the Complejo Hospitalario Insular-Materno Infantil de Canarias, between 2005 and 2014. Results Recurrence was observed in 81 patients (10.04% of the sample); 66.7% of them suffered relapse within 2 years and 80.2% within 3 years after the termination of the primary treatment; 41.9% showed distant metastases while the rest corresponded to local-regional (40.7%) or ganglionar (17.4%) relapse; 42% of these were symptomatic; 14 patients showed more than 1 site of relapse. Relapse was detected mainly through symptoms and physical examination findings (54.3%), followed by elevated serummarker levels (29.6%), computed tomography (CT) images (9.9%) and abnormal vaginal cytology findings (6.2%). No differences in global survival were found between patients with symptomatic or asymptomatic relapse. Conclusion Taking into account that the recurrence rate of endometrial cancer is low, that relapse occurs mainly within the first 3 years post-treatment and that symptom evaluation and physical examination are the most effective follow-up methods, we postulate that a modification of the current model of hospital follow-up should be considered.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Protocolos Clínicos
/
Neoplasias do Endométrio
/
Carcinoma Endometrioide
/
Recidiva Local de Neoplasia
Tipo de estudo:
Guia de Prática Clínica
/
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Rev. bras. ginecol. obstet
Assunto da revista:
Ginecologia
/
Obstetrícia
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Índia
/
Espanha
Instituição/País de afiliação:
Complejo Hospitalario Universitario Insular Materno-Infantil/ES
/
Hospital Dr. Negrin/ES
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