Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism
Arch. endocrinol. metab. (Online)
;
65(2): 212-230, Mar.-Apr. 2021. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1248814
ABSTRACT
ABSTRACT Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment of hypopituitarism, has increased the prevalence of this condition. Pituitary hormone deficiencies can induce significant clinical changes with consequent increased morbidity and mortality rates, while hormone replacement based on current guidelines protects these patients. In this review, we will first discuss the different etiologies of hypopituitarism and then address one by one the clinical aspects, diagnostic evaluation, and therapeutic options for deficiencies of TSH, ACTH, gonadotropin, and GH. Finally, we will detail the hormonal interactions that occur during replacement of pituitary hormones.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Endocrinologia
/
Hipopituitarismo
Tipo de estudo:
Guia de Prática Clínica
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Arch. endocrinol. metab. (Online)
Assunto da revista:
Endocrinologia
/
Metabolismo
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
A.C. Camargo Cancer Center/BR
/
Santa Casa de Belo Horizonte/BR
/
Universidade Estadual de Campinas/BR
/
Universidade Federal de Pernambuco/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Ceará/BR
/
Universidade Federal do Paraná/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade Federal do Rio de Janeiro/BR
/
Universidade de Brasília/BR
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