Prevalence and risk factors for post-traumatic stress, anxiety, and depression in sepsis survivors after ICU discharge
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
43(3): 269-276, May-June 2021. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1249196
ABSTRACT
Objective:
Sepsis survivors present a wide range of sequelae; few studies have evaluated psychiatric disorders after sepsis. The objective of this study was to define the prevalence of and risk factors for anxiety, depression and post-traumatic stress disorder (PTSD) symptoms in sepsis survivors.Method:
Anxiety, depression and post-traumatic stress symptoms in severe sepsis and septic shock survivors 24 h and 1 year after intensive care unit (ICU) discharge were assessed using the Beck Anxiety/Depression Inventories and the PTSD Checklist-Civilian Version. Differences in psychiatric symptoms over time and the influence of variables on these symptoms were calculated with marginal models.Results:
A total of 33 patients were enrolled in the study. The frequencies of anxiety, depression and PTSD 24 h after ICU discharge were 67%, 49%, and 46%, respectively and, among patients re-evaluated 1 year after ICU discharge, the frequencies were 38%, 50%, and 31%, respectively. Factors associated with PTSD included serum S100B level, age, and Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) score. Factors associated with depression included patient age and cumulative dose of dobutamine. IQCODE score and cumulative dose of haloperidol in the ICU were associated with anxiety after ICU discharge.Conclusion:
Patients who survive sepsis have high levels of psychiatric symptoms. Sepsis and associated treatment-related exposures may have a role in increasing the risk of subsequent depression, anxiety, and PTSD.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Transtornos de Estresse Pós-Traumáticos
/
Sepse
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Escola de Medicina, Universidade Federal de Ouro Preto (UFOP)/BR
/
Faculdade de Medicina, UFMG/BR
/
Programa de Pós-Graduação em Ciências da Saúde, Infectologia e Medicina Tropical (PPG-IMT), Universidade Federal de Minas Gerais (UFMG)/BR
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