Clinical and epidemiological aspects of Candidemia in eight medical centers in the state of Parana, Brazil: Parana Candidemia Network
Braz. j. infect. dis
;
25(1): 101041, jan., 2021. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1249290
ABSTRACT
ABSTRACT Objectives:
Candida spp. has been reported as one of the common agents of nosocomial bloodstream infections and is associated with a high mortality. Therefore, this study evaluated the clinical findings, local epidemiology, and microbiological aspects of candidemia in eight tertiary medical centers in the state of Parana, South of Brazil.Methods:
In this study, we reported 100 episodes of candidemia in patients admitted to eight different hospitals in five cities of the state of Parana, Brazil, using data collected locally (2016 and 2017) and tabulated online.Results:
The incidence was found to be 2.7 / 1000 patients / day and 1.2 / 1000 admissions. C. albicans was responsible for 49% of all candidemia episodes. Cancer and surgery were the two most common underlying conditions associated with candidemia. The mortality rate within 30 days was 48%, and removal of the central venous catheter (p = 0.029) as well as empirical or prophylactic exposure to antifungals were both related to improved survival (p = 0.033).Conclusions:
This study highlights the high burden and mortality rates of candidemia in hospitals from Parana as well as the need to enhance antifungal stewardship program in the enrolled medical centers.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecção Hospitalar
/
Incidência
/
Candidemia
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Hospital Erasto Gaertner/BR
/
Hospital Santa Casa de Maringá/BR
/
Hospital Universitário Regional Norte/BR
/
Hospital Universitário do Oeste do Paraná/BR
/
Hospital Universitário dos Campos Gerais/BR
/
Hospital do Câncer UOPECCAN/BR
/
Hospital do Câncer de Londrina/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Paraná/BR
Similares
MEDLINE
...
LILACS
LIS