Assessment of the Efficacy of Ankaferd Blood Stopper on the Prevention of Postoperative Pericardial Adhesions : Cardiovascular Topic
Cardiovasc. j. Afr. (Online)
; 25(3): 100-105, 2014.
Article
em En
| AIM
| ID: biblio-1260436
Biblioteca responsável:
CG1.1
ABSTRACT
Objectives:
Ankaferd has been used as a blood-stopping agent and it may also have an anti-inflammatory effect. We investigated the efficacy of Ankaferd in preventing postoperative pericardial adhesions in an experimental rabbit model.Methods:
Sixteen New Zealand white rabbits were used and categorised into two groups an Ankaferd and a control group. The Ankaferd group of rabbits was treated with a sponge impregnated with Ankaferd solution; which was applied over the abraded epicardium. A sponge impregnated with 0.9 isotonic NaCl solution was applied to the control group using the same protocol. Scores for adhesion and visibility of coronary vessels were graded by macroscopic examination; and pericardial tissues were analysed microscopically in terms of inflammation and fibrosis.Results:
In the Ankaferd group; the adhesion scores were significantly higher than in the control group (p = 0.007).When the groups were compared according to the prevalence of fibrosis and degree of inflammation; the Ankaferd group was found to be statistically significantly different from the control group in terms of prevalence of fibrosis (p = 0.028).Conclusion:
Topical application of Ankaferd to prevent postoperative pericardial adhesions increased adhesion and fibrosis scores
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Índice:
AIM
Assunto principal:
Complicações Pós-Operatórias
/
Aderências Teciduais
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Cardiovasc. j. Afr. (Online)
Ano de publicação:
2014
Tipo de documento:
Article