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Comparative evaluation of carotid intima media thickness in paediatric type 1 diabetic children and healthy children in Ibadan and Lagos, Nigeria
Nuhu, A. C; Agunloye, A. M; Jarrett, O. O; Oduwole, A.
  • Nuhu, A. C; s.af
  • Agunloye, A. M; s.af
  • Jarrett, O. O; s.af
  • Oduwole, A; s.af
Artigo em Inglês | AIM | ID: biblio-1261224
ABSTRACT
Patients with type 1 diabetes are at greater risk of cardiovascular disease and atherosclerosis. Carotid in-tima­media thickness (CIMT) measured by ultrasound is a marker of atherosclerosis and can predict future cardiovascular events.The aim of this study was to measure the CIMT in paediatric type 1 diabetes patients in Ibadan and Lagos and compare results with the CIMT of non-diabetic healthy control children. Carotid ultrasound was performed and CIMT measured in 70 subjects (35 diabetic patients and 35 non-diabetic controls matched for age and sex). Mean age was 12.8±3.2 years. A slightly higher, but non-significant mean CIMT was seen in diabetic cases mean values in type 1 diabetes patients were 0.475±0.068 and 0.476±0.069 (right and left respectively) while in controls, mean values were 0.467±0.064 and 0.468±0.054 (p=0.618 and 0.575 respectively). The CIMT in both groups correlated positively with age and body mass index (BMI). Significantly higher mean CIMT values were seen in males with type 1 diabetes on both sides. However, there was no significant correlation between CIMT and duration of illness, insulin dosage, or blood pressure. CIMT is a safe and convenient measurement, which may be helpful in predicting an increased risk of future cardiovascular disease in children with type 1 diabetes
Assuntos
Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Lagos / Criança / Saúde da Criança / Diabetes Mellitus Tipo 1 / Espessura Intima-Media Carotídea / Nigéria Tipo de estudo: Estudo prognóstico País/Região como assunto: África Idioma: Inglês Revista: Afr. ed.) Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Lagos / Criança / Saúde da Criança / Diabetes Mellitus Tipo 1 / Espessura Intima-Media Carotídea / Nigéria Tipo de estudo: Estudo prognóstico País/Região como assunto: África Idioma: Inglês Revista: Afr. ed.) Ano de publicação: 2017 Tipo de documento: Artigo