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Determining seroprevalence of Hepatitis B and C virus infections and associated risk factors among apparently healthy mothers in Addis Ababa, Ethiopia
Biazin, Habtamu; Teshome, Seifegebriel; Ayenew, Zeleke; Abebe, Tamrat; Mihret, Adane; Aseffa, Abraham; Howe, Rawleigh.
  • Biazin, Habtamu; s.af
  • Teshome, Seifegebriel; s.af
  • Ayenew, Zeleke; s.af
  • Abebe, Tamrat; s.af
  • Mihret, Adane; s.af
  • Aseffa, Abraham; s.af
  • Howe, Rawleigh; s.af
Ethiop. med. j. (Online) ; 57(3): 129-138, 2019. ilus
Artigo em Inglês | AIM | ID: biblio-1262022
ABSTRACT

Introduction:

Viral hepatitis is a global public health problem affecting millions of people every year, causing disability and death. Hepatitis B (HBV) and hepatitis C (HCV) viruses spread horizontally, mainly through sexual contact and contaminated needles, and vertically. Both cause considerable morbidity and mortality worldwide. Maternal infection is a risk factor for vertical transmission.

Objective:

To determine the sero-prevalence of HBsAg and anti-HCV antibody among non-pregnant, apparently healthy mothers and to identify potential risk factors associated with HBV or HCV infection.

Methods:

A community based cross sectional study was conducted on 454 apparently healthy women, in Addis Ababa, Ethiopia from May 2016 to June 2017. A systematic random sampling method was used to recruit participants.

Result:

A total of 454 mothers were enrolled. Sero-prevalence of HBsAg and HCV was found to be 3.7% and 2.0%, respectively. HBc antibody was detected in 36.3% of the mothers. None of the participants were co-infected with both viruses. Previous history of liver disease, history of jaundice, HIV infection, and family history of liver disease were significantly associated with HBV infection. Marital status, caring for hepatitis patients, and a history of liver disease were factors significantly associated with HCV infection.

Conclusion:

Apparently healthy mothers in Addis Ababa had intermediate level of endemicity for hepatitis B and C infections Routine screening and vaccination of high risk reproductive mothers against HBV is advisable. Emphasis should be given to health education and promotion of infection control practices. Population based studies are strongly recommended to help monitor disease transmission patterns and to design evidence-based interventions against the spread of hepatitis infections in Ethiopia
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Índice: AIM (África) Assunto principal: Hepatite C / Etiópia / Hepatite B / Hepatite Viral Humana / Mães Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco País/Região como assunto: África Idioma: Inglês Revista: Ethiop. med. j. (Online) Ano de publicação: 2019 Tipo de documento: Artigo

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Índice: AIM (África) Assunto principal: Hepatite C / Etiópia / Hepatite B / Hepatite Viral Humana / Mães Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco País/Região como assunto: África Idioma: Inglês Revista: Ethiop. med. j. (Online) Ano de publicação: 2019 Tipo de documento: Artigo