Quantitative Analysis of Gallstones in Libyan Patients
Libyan j. med
;
5: 1-6, 2009. tables
Artigo
em Inglês
| AIM
| ID: biblio-1265106
ABSTRACT
Gallstone disease is one of the major surgical problems in the Libyan population; it is probably related to diet; especially excessive consumption of meat. The study was conducted to determine the composition of gallstones and their possible etiology in a Libyan population. The chemical composition of gallstones from 41 patients (six males and 35 females) was analyzed. The stones were classified into cholesterol; pigment; and mixed stones (MS). Cholesterol stones (CS) showed a significantly higher cholesterol content than pigment stones (PS) (p=0.0085) though not significantly higher than MS. Their phospholipid content and inorganic phosphates were higher than in the other types of stones and oxalate content was significantly elevated in comparison with MS (p=0.0471). In MS; the cholesterol; bile acids; and bilirubin were intermediate between cholesterol and PS; whereas triglycerides were significantly more than PS (p=0.0004). Bilirubin (0.0001) and bile acids (p=0.0009) were significantly higher than CS (p=0.0001). However; they contained the lowest amounts of sodium; potassium; magnesium; and oxalate. In PS; bilirubin (p=0.0001) was significantly higher than both groups. Bile acid content was significantly higher than CS (p=0.0001) but not significantly more than MS. They showed the highest values of calcium; sodium; potassium; magnesium; and chlorides compared to the other types of stones. High levels of cholesterol in stones and dyslipidemia associated with mixed as well as cholesterol gallstones suggest an etiological association and efforts to reduce dietary fat among the Libyan population may lead to decreased cholesterol and mixed gallstones
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Cálculos Biliares
/
Colesterol
Limite:
Humanos
Idioma:
Inglês
Revista:
Libyan j. med
Ano de publicação:
2009
Tipo de documento:
Artigo
Instituição/País de afiliação:
Department of Biochemistry, Faculty of Medicine, Al-Arab Medical University/LY
/
Department of Surgery, Faculty of Medicine, Al-Arab Medical University/LY
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