A preliminary report on the Anti-Diarrhoeal benefit of Seleru: A possible adjunct HIV/AIDS Therapy

ABSTRACT

"Infection with the human immunodeficiency Virus (HIV) is assuming greater proportion. The global estimates of new infections keep rising. The cure for HIV infection/acquired immunodeficiency syndrome is related to the socio-economic status of the population. In our environment; poverty is a major undoing in the medical management of HIV/AIDS using orthodox antiretroviral drugs. Consequently; great attention is being turn to the exploration of herbal remedies in the management of this dreaded disorder. A concoction ""Seleru"" (Amodmat r) is claimed to have benefits for HIV/AIDS. We investigated the role of this concoction on diarrhoea; a distressing symptom of the syndrome. The antidiarrhoeal property of ""Seleru"" (Amodmat r) was investigated using the charcoal meal preparation; on albino wistar rat. The extract was administered at a dose range of between 100mg/kg to 800mg/kg body weight. Results show an antimotility effect on the gastrointestinal tract; supporting a usefulness of the extract in diarrhoeal states."