Invasive pneumococcal disease in a cohort of HIV-1 infected female prostitutes living in Nairobi
Proceedings of the KEMRI/KETRI Annual Medical Scientific Conference
;
13(1): 30-33, 1992.
Artigo
em Inglês
| AIM
| ID: biblio-1268782
ABSTRACT
A cohort of predominantly HIV seropositive female prostitutes has been followed for a two year period. 54 episodes of invasive pneumococcal disease (ISpD) have been diagnosed in 41 patients; of which 28 were bacteraemic. All patients were seropositive for HIV. Pneumonia was the most common presentation in 34(64); then maxillary sinusitis in 11 (21) and occult bacteraemia in 8 (15). Nine of the patients (22) had proven recurrent disease despite appropriate therapy; most of these episodes were with different serotypes suggesting that this is reinfection rather than relapse. The mean CD4 count of first episode ISpD was 325 showing that that this is an early HIV-related problem. The estimated inicdence rate was 30/1000 person years of observation and it was the most common life-threatening problem seen in the cohort in the study period. All patients survived with standard penicillin or ampicillin treatment. The pneumococcus is an important but under-recognised cause of HIV-related disease in Africa. Presentation can be atypical but the response to appropriate therapy good
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Índice:
AIM (África)
Assunto principal:
Infecções Pneumocócicas
/
Trabalho Sexual
/
Infecções por HIV
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
KETRI Annual Medical Scientific Conference
Ano de publicação:
1992
Tipo de documento:
Artigo
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