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Circurating trypanosomal antigen levels in sleeping sickness patients under going treatment at Alupe
Igweh, A. C; Mbwabi, D; Ngaira, J. M; Njenga, J. N; Nyang'ao, J. M. N; Olaho-Mukani, W; Omuse, J. K; Tengekyon, K. M.
  • Igweh, A. C; s.af
  • Mbwabi, D; s.af
  • Ngaira, J. M; s.af
  • Njenga, J. N; s.af
  • Nyang'ao, J. M. N; s.af
  • Olaho-Mukani, W; s.af
  • Omuse, J. K; s.af
  • Tengekyon, K. M; s.af
Artigo em Inglês | AIM | ID: biblio-1268805
ABSTRACT
Sera from 99 sleeping sickness patients admitted to Alupe Hospital were analyzed for circulating trypanosomal antigens using a sandwich antigen-trapping enzyme immunosorbent assay. Trypanosomal antigens were detected in 83 (84) of the patients. Post-treatment antigen profile in 67 patients showed five distinct patterns in 48 of the patients antigen levels remained elevated thoughout; in 31 of the patients antigens dropped to the; negative value; and became elevated afterward; in 6.0 of the patients antigen levels were negative initially; but became elevated later; in 7.5 of the patients antigen levels remained below the negative value thoughout. The significance of these observations in the clinical management of sleeping sickness is discussed
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Índice: AIM (África) Assunto principal: Tripanossomíase / Antígenos Idioma: Inglês Revista: KETRI Annual Medical Scientific Conference Ano de publicação: 1992 Tipo de documento: Artigo

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Índice: AIM (África) Assunto principal: Tripanossomíase / Antígenos Idioma: Inglês Revista: KETRI Annual Medical Scientific Conference Ano de publicação: 1992 Tipo de documento: Artigo