Circurating trypanosomal antigen levels in sleeping sickness patients under going treatment at Alupe
Proceedings of the KEMRI/KETRI Annual Medical Scientific Conference
;
13(2): 139-143, 1992.
Artigo
em Inglês
| AIM
| ID: biblio-1268805
ABSTRACT
Sera from 99 sleeping sickness patients admitted to Alupe Hospital were analyzed for circulating trypanosomal antigens using a sandwich antigen-trapping enzyme immunosorbent assay. Trypanosomal antigens were detected in 83 (84) of the patients. Post-treatment antigen profile in 67 patients showed five distinct patterns in 48 of the patients antigen levels remained elevated thoughout; in 31 of the patients antigens dropped to the; negative value; and became elevated afterward; in 6.0 of the patients antigen levels were negative initially; but became elevated later; in 7.5 of the patients antigen levels remained below the negative value thoughout. The significance of these observations in the clinical management of sleeping sickness is discussed
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Índice:
AIM (África)
Assunto principal:
Tripanossomíase
/
Antígenos
Idioma:
Inglês
Revista:
KETRI Annual Medical Scientific Conference
Ano de publicação:
1992
Tipo de documento:
Artigo
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