Updating zika diagnostic methods: the point-of-care approach
Rev. invest. clín
;
72(6): 344-352, Nov.-Dec. 2020. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1289729
ABSTRACT
Abstract Zika virus (ZIKV) has gained great importance worldwide since the past epidemic that occurred in 2015 in Brazil. Early identification of ZIKV is critical to minimize transmission and prevents potentially devastating consequences, including microcephaly in neonates of infected women, congenital blindness, or Guillain-Barré Syndrome. However, this is not an easy task, considering that approximately 80% of ZIKV infection cases are asymptomatic or oligosymptomatic, there are diverse modes of transmission (vertical transmission is through vectors and horizontal transmission through blood, saliva, semen, and urine from infected people), and the fact that ZIKV has a high identity percentage with other cocirculating Flaviviruses such as dengue. Here, we review ZIKV diagnostic methods, with special emphasis on the development of point-of-care diagnostic assays, since these devices commonly have two important advantages they provide prompt screening and are affordable.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Sistemas Automatizados de Assistência Junto ao Leito
/
Infecção por Zika virus
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. invest. clín
Assunto da revista:
Medicina
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
Center for Research and Assistance in Technology and Design of the State of Jalisco/MX
/
Consejo Nacional de Ciencia y Tecnología (CONACyT) - Medical and Pharmaceutical Biotechnology Unit/MX
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