Comparison of two commercial tests (Immy vs. Dynamiker) for cryptococcal capsular antigen
Rev. Soc. Bras. Med. Trop
;
54: e03072021, 2021. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1340825
ABSTRACT
Abstract INTRODUCTION Lateral flow assay is an advanced method useful in the early diagnosis of cryptococcal meningitis. We aimed to compare two commercial tests for cryptococcal capsular antigen in the sera of asymptomatic patients with human immunodeficiency virus in Barranquilla, Colombia. METHODS Thawed (n=162) previously collected serums (2016-2019) were processed using IMMY and Dynamiker cryptococcal antigen lateral flow assay. RESULTS Compared to IMMY's results, Dynamiker's sensitivity, specificity, positive predictive value, negative predictive value, and kappa index were 100%, 89.9%, 48.3%, 100.0%, and 0.61, respectively. CONCLUSIONS The Dynamiker test had excellent sensitivity, acceptable specificity, and a low detection threshold for cryptococcal antigen in the tested samples.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções por HIV
/
Meningite Criptocócica
/
Cryptococcus
Tipo de estudo:
Estudo prognóstico
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Colômbia
Instituição/País de afiliação:
Instituto Nacional de Salud/CO
/
Universidad Metropolitana/CO
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