Coagulopatía asociada a síndrome de malabsorción por enfermedad celíaca / Coagulopathy associated with celiac disease malabsorption syndrome
Rev. méd. Maule
;
36(2): 44-49, dic. 2020. ilus
Artigo
em Espanhol
| LILACS
| ID: biblio-1344614
ABSTRACT
This article describes a 19-y-old patient with abdominal pain and signs of malnutrition. She had been treated previously with an antibiotic for chronic diarrhea. Laboratory analyses showed the presence mild hypoalbuminemia, and considerably prolonged prothrombin time. Tests revealed that hemostasis improved after the patient received fresh frozen plasma and vitamin k. A coagulation profile showed a decrease in clotting factors V, VII, IX, and fibrinogen. Positive serology (immunoglobulin A antitissue transglutaminase and immunoglobulin A antiendomysial antibodies) and small bowel mucosal histopathology confirmed the presence of celiac disease (CD). The girl recovered completely after she was put on a gluten-free diet. Vitamin Kdeficiency is a rare complication that occurs in celiac disease manifestations. In addition to antibiotic therapy, treatment with other drugs that influence vitamin K resorption and metabolism may increase the risk of bleeding in patients with CD with hypoprothrombinemia.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Transtornos da Coagulação Sanguínea
/
Doença Celíaca
Tipo de estudo:
Estudo diagnóstico
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Maule
Assunto da revista:
Medicina
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
CESFAM Las Américas/CL
/
Regional de Talca/CL
/
Universidad de Talca/CL
Similares
MEDLINE
...
LILACS
LIS