Physical exercise in sickle cell anemia: a systematic review
Hematol., Transfus. Cell Ther. (Impr.)
;
43(3): 324-331, July-Sept. 2021. tab, ilus
Artigo
em Inglês
| LILACS
| ID: biblio-1346253
ABSTRACT
Introduction and objective: Sickle cell anemia (SCA) is a genetic condition that alters the conformation of deoxygenated red blood cells, which results in their stiffening and the occurrence of vaso-occlusive crises, endothelium damage, organ dysfunction and systemic complications. Additionally, SCA limits the participation of individuals in physical and social activities. As we consider that physical exercise promotes the recovery of functional capacity and cardiorespiratory conditioning, we aim to verify the patterns of prescription, the effects and safety of exercise for individuals with SCA. Methodology: We systematically reviewed the published literature focusing on clinical trials that correlated physical exercise with SCA patients and cross-sectional studies that applied the stress test. The data research was based on the PRISMA recommendations and the following databases were used: Medline by PubMed, Cochrane, PEDro, Scielo. Results: Six studies which were based on the evaluation of 212 patients aged between 13 and 40 years, were selected from 122 identified studies. Those studies associated the individual effort tolerance improvement, its inflammatory profile adjustment and the absence of alteration in the autonomic nervous system activity to physical exercise or stress test. Conclusion: Low-to-moderate intensity physical exercise increased the SCA individual tolerance without causing vaso-occlusive crises, nor changes in the hemorheological and inflammatory profiles.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Exercício Físico
/
Anemia Falciforme
Tipo de estudo:
Guia de Prática Clínica
/
Estudo observacional
/
Fatores de risco
/
Revisões Sistemáticas Avaliadas
Limite:
Adolescente
/
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Hematol., Transfus. Cell Ther. (Impr.)
Assunto da revista:
Hematologia
/
TransfusÆo de Sangue
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Actus Cordios Reabilitação Cardiovascular, Respiratória e Metabólica/BR
/
Escola Bahiana de Medicina e Saúde Pública/BR
/
Faculdade Adventista da Bahia - FADBA/BR
/
Fundação Estatal de Saúde da Família - FESF-SUS/BR
/
Hospital Encore/BR
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