Prolonged SARS-CoV-2 RNA shedding in a young man recovering from traumatic pneumothorax
S. Afr. med. j
;
112(2): 81-85, 2022.
Artigo
em Inglês
| AIM
| ID: biblio-1358373
ABSTRACT
We describe a case of prolonged SARS-CoV-2 RNA shedding in an HIV-negative 21-year-old man recovering from abdominal and thoracic trauma. Nasopharyngeal (NP) swabs collected at 12 time points over a 95-day span all tested positive for SARS-CoV-2 by reverse transcription polymerase chain reaction (RT-PCR). Genotyping revealed canonical beta-variant E484K and N501Y mutations at earlier time points. Human rhinovirus, coronavirus NL63 and respiratory syncytial virus B were detected at different time points by RT-PCR. Full blood analysis at time point 9 (day 82) showed leukopenia with lymphocytosis. The patient's NP swab tested negative for SARS-CoV-2 by RT-PCR 101 days after the first positive test. The prolonged duration of SARS-CoV-2 RNA shedding in the context of trauma presented here is unique and has important implications for COVID-19 diagnosis, management and policy guidelines
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Pneumotórax
/
Teste de Ácido Nucleico para COVID-19
/
SARS-CoV-2
/
COVID-19
Tipo de estudo:
Guia de Prática Clínica
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
S. Afr. med. j
Ano de publicação:
2022
Tipo de documento:
Artigo
Instituição/País de afiliação:
Ndlovu Laboratories, Elandsdoorn/ZA
/
Ndlovu Laboratories, Elandsdoorn, Limpopo Province/ZA
/
Ndlovu Research Consortium, Elandsdoorn/ZA
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