Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
Rev. Assoc. Med. Bras. (1992)
;
68(1): 87-93, Jan. 2022. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1360707
ABSTRACT
SUMMARY OBJECTIVE:
The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury.METHODS:
Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively.RESULTS:
Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher.CONCLUSIONS:
As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Traumatismo por Reperfusão
/
Cynara scolymus
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. Assoc. Med. Bras. (1992)
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Ankara Training and Research Hospital/TR
/
Ankara Yıldırım Beyazıt University/TR
/
Gülhane Training and Research Hospital/TR
/
Selçuk University/TR
/
TOBB University of Economics & Technology/TR
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