Trigeminal Cave Brain Metastasis from Prostate Adenocarcinoma: Case Report and Review of the Literature
Arq. bras. neurocir
;
37(4): 330-333, 15/12/2018.
Artigo
em Inglês
| LILACS
| ID: biblio-1362652
ABSTRACT
The present study presents the case of a 66-year-old patient diagnosed with prostate adenocarcinoma 4 years earlier and treated with prostatectomy, radiotherapy, chemotherapy and hormonetherapy but still displaying high prostate-specific antigen (PSA) levels. The patient complaints were double vision and headaches. Upon physical examination, he displayed 6th cranial nerve paresis and 5th cranial nerve paresthesia. Amagnetic resonance imaging (MRI) exam was performed, which revealed a mass on the right trigeminal cave. The patient underwent surgical removal of the tumor, and the pathological analysis of the specimen established metastatic prostate cancer as the diagnosis. Brainmetastases fromprostate cancer are extremely rare and mark advanced disease, with immune system failure and blood-brain barrier breach. Prostate-specific antigen levels do not correlate with the possibility of metastatic disease. Prostate adenocarcinoma is the histologic typemost commonly associated with brainmetastases,with themeninges being more frequently affected, followed by the brain parenchyma. The neurological symptoms more often displayed are non-focal, such as headaches and mental confusion. Surgery associated with radiotherapy is the most validated treatment.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Neoplasias da Próstata
/
Nervo Trigêmeo
/
Adenocarcinoma
/
Antígeno Prostático Específico
Tipo de estudo:
Estudo diagnóstico
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Arq. bras. neurocir
Assunto da revista:
Cirurgia
/
Neurocirurgia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Department of Neurosurgery, Hospital da Cidade de Passo Fundo/BR
/
Department of Oncology, Hospital da Cidade de Passo Fundo/BR
/
Faculty of Medicine, Centro Universitário Assis Gurgacz/BR
/
Faculty of Medicine, Universidade de Passo Fundo/BR
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