Effect of rape flower on benign prostatic hyperplasia in rats
Braz. J. Pharm. Sci. (Online)
; 58: e18785, 2022. graf
Article
em En
| LILACS
| ID: biblio-1364421
Biblioteca responsável:
BR40.1
Localização: BR40.1
ABSTRACT
We were carried out to investigate the efficacy of Rape (Rapeseed, Brassica napus L.) flower on BPH (benign prostatic hyperplasia) in rats. We found that the extract from Rape flower prevented hyperplasia in testosterone-induced BPH model, the relevant animal model of human BPH. Extract reduced the weight of prostate and induced significantly cell apoptosis in prostate in BPH model. In addition, the extract controlled expression of TGF-ß1 in prostate gland and promoted urinary output in dose-dependence in BPH model. Our data provide that Rape flower may be useful for treatment of BPH
Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Hiperplasia Prostática
/
Eficácia
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Brassica napus
/
Flores
Limite:
Animals
Idioma:
En
Revista:
Braz. J. Pharm. Sci. (Online)
Assunto da revista:
Farmacologia
/
Teraputica
/
Toxicologia
Ano de publicação:
2022
Tipo de documento:
Article