Comparison of Oncostatin M in Patients with Chronic Periodontitis with and without Diabetes
Pesqui. bras. odontopediatria clín. integr
;
22: e210136, 2022. tab
Artigo
em Inglês
| LILACS, BBO
| ID: biblio-1365223
ABSTRACT
Abstract Objective:
To compare the Oncostatin M (OSM) concentrations in tissues of patients with chronic periodontitis with and without diabetes. Material andMethods:
Sixty-four subjects visiting the dental outpatient department were categorized as "healthy" (Group 1), "periodontitis" (Group 2), and "diabetes with periodontitis" (Group 3) groups. The clinical oral examination included assessment of plaque, gingivitis, probing depth, clinical attachment level. Blood glucose was assessed for group 3 patients. OSM concentration in the tissues was assessed using ELISA in all groups.Results:
The mean OSM was 0.02 ± 0.04 pg/mg in the healthy group, 0.12 ± 0.09 pg/mg in the chronic periodontitis group and 0.13 ± 0.10 pg/mg in the diabetes-periodontitis group. A significantly higher mean OSM was seen in Group 2 and Group 3 than Group 1. The amount of OSM positively correlated with probing depth and clinical attachment level.Conclusion:
Periodontal disease causes a rise in Oncostatin M, independent of the diabetic status. Expression of OSM in the gingival tissues can serve as an inflammatory marker.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Índice de Placa Dentária
/
Citocinas
/
Diabetes Mellitus
/
Oncostatina M
/
Periodontite Crônica
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Pesqui. bras. odontopediatria clín. integr
Assunto da revista:
Odontologia
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Índia
Instituição/País de afiliação:
Manipal Academy of Higher Education/IN
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