Analysis of high-intensity interval training on bone mineral density in an experimental model of type 2 diabetes
Acta cir. bras
;
37(2): e370207, 2022. tab, graf, ilus
Artigo
em Inglês
| LILACS, VETINDEX
| ID: biblio-1374069
ABSTRACT
Purpose:
To analyze the effect of high-intensity interval training (HIIT) on bone mineral density (BMD) in a model of type 2 diabetes mellitus.Methods:
Thirty-two male, adult, 12-week-old rats (Rattus norvegicus), of the Wistar lineage, were used. The animals induced to the experimental model received a high fat diet for 10 days and, after that period, intraperitoneal injection of streptozotocin (40 mg·kg1), dissolved in 20 mmol·L1 sodium citrate solution (pH = 4.5). The experimental group of diabetes was formed by the animals that, 48 h after the injection of streptozotocin, had fasting blood glucose > 250 mg·dL1). The animals were randomly divided into four groups with eight animals each HIIT experimental diabetes; HIIT control; sedentary experimental diabetes and sedentary control. The animals in the HIIT group performed an aerobic exercise protocol on a treadmill inclined at an angle of 15° to the horizontal, with interspersed intensity. Five weekly sessions, lasting 49 min each, were held for 6 weeks. The analysis of cortical bone density (CBD) and BMD were performed by X-ray images using the In-Vivo Xtreme II/Bruker system.Results:
For CBD and BMD, when comparing diabetes and control groups, a significant difference was seen between groups in relation to HIIT (p = 0.007). Animals submitted and not submitted to HIIT in the same group showed a significant difference between groups in relation to diabetes (p < 0.001).Conclusions:
The HIIT experimental diabetes group had increased CBD and BMD in comparison with the sedentary experimental diabetes group.Assuntos
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Osteoporose
/
Densidade Óssea
/
Diabetes Mellitus Experimental
/
Diabetes Mellitus Tipo 2
/
Treinamento Intervalado de Alta Intensidade
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Ano de publicação:
2022
Tipo de documento:
Artigo
Instituição/País de afiliação:
Universidade Federal do Mato Grosso do Sul/BR
Similares
MEDLINE
...
LILACS
LIS