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Papillary cystadenoma of the epididymis
Lopez, Olga; Bahmad, Hisham F.; Delgado, Ruben; Cordon, Billy H.; Poppiti, Robert; Howard, Lydia.
  • Lopez, Olga; Florida International University. Herbert Wertheim College of Medicine. Miami. US
  • Bahmad, Hisham F.; Mount Sinai Medical Center. Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine. Miami Beach. US
  • Delgado, Ruben; Mount Sinai Medical Center. Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine. Miami Beach. US
  • Cordon, Billy H.; Mount Sinai Medical Center. Division of Urology. Miami Beach. US
  • Poppiti, Robert; Florida International University. Herbert Wertheim College of Medicine. Miami. US
  • Howard, Lydia; Florida International University. Herbert Wertheim College of Medicine. Miami. US
Autops. Case Rep ; 12: e2021374, 2022. graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1374497
ABSTRACT
ABSTRACT Background Papillary cystadenoma is a rare benign neoplasm of the epididymis. It may occur sporadically or in association with von Hippel-Lindau disease (VHLD). Papillary cystadenoma of the epididymis (PCE) is a benign mimic of metastatic clear cell renal cell carcinoma (CCRCC) given their histologic similarities. Case presentation Herein, we present the case of a 40-year-old man with a four-year history of microhematuria and a recently detected right paratesticular mass. A testicular sonogram revealed a hypoechoic, hypervascular solid mass in the right epididymal head treated by surgical excision. Histopathological examination demonstrated a 1.1 cm papillary cystadenoma of the epididymis. Genetic testing performed later showed no signs of VHLD. However, heterozygous mutations in three genes - CASR, POT1, and RAD51D - were found which have never been reported in PCE before. Conclusions Papillary cystadenoma of the epididymis should always be considered in the differential diagnosis of epididymal lesions, especially those that are cystic. The mainstay of treatment remains surgical excision, which provides an excellent prognosis.


Texto completo: DisponíveL Índice: LILACS (Américas) Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2022 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Florida International University/US / Mount Sinai Medical Center/US

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Texto completo: DisponíveL Índice: LILACS (Américas) Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2022 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Florida International University/US / Mount Sinai Medical Center/US