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Mortalidad en pacientes hospitalizados por COVID-19. Estudio prospectivo en el norte del Perú, 2020 / Mortality in patients hospitalized with COVID-19 in northern Peru
León-Jiménez, Franco; Vives-Kufoy, Camila; Failoc-Rojas, Virgilio E; Valladares-Garrido, Mario J.
  • León-Jiménez, Franco; Hospital Santa Rosa Piura. Departamento Medicina Interna. Piura. PE
  • Vives-Kufoy, Camila; Sanidad del Grupo 7-FAP. Piura. PE
  • Failoc-Rojas, Virgilio E; Universidad San Ignacio de Loyola. Lima. PE
  • Valladares-Garrido, Mario J; Universidad Norbert Wiener. Vicerrectorado de Investigación. Lima. PE
Rev. méd. Chile ; 149(10): 1459-1466, oct. 2021. tab
Artigo em Espanhol | LILACS | ID: biblio-1389373
ABSTRACT

BACKGROUND:

Peru has one of the highest mortality rates due to COVID-19 in the world.

AIM:

To describe the clinical features, evolution and explore factors associated with mortality in patients with moderate to severe Covid-19. MATERIAL AND

METHODS:

Prospective analytical study. The clinical, laboratory, imaging, and mortality data of patients admitted at a COVID service of the Santa Rosa de Piura Hospital were recorded from April to June 2020.

RESULTS:

Data from 391 patients with a median age of 60 years (70% women) was gathered. The time lapse between the onset of the disease and hospitalization was seven days. The most common alteration in the blood count was Neutrophilia in 78% of patients. The median PaO2/FiO2 ratio was 77. The distribution of tomographic patterns was Ground glass in 91% of patients, interstitial involvement in 57%, consolidation in 43%. Sixteen percent of patients had at least one complication, the most common was an increase in transaminases in 2%. Four percent were admitted to the intensive care unit and 53% died (94% during hospitalization and 5.8% during ICU stay). In the bivariate analysis, an association was found between a higher mortality and older age (p = 0.01), having fewer days of illness (p = 0.03), fewer days of hospital stay (p < 0.01), having at least one comorbidity (p = 0.02), lymphopenia (p = 0.02), neutrophilia (P = 0.03) and lower PaO2/ FiO2 ratio (p < 0.01).

CONCLUSIONS:

Fifty percent of these patients died. Age, rapid progression, having comorbidities and other laboratory alterations were associated with mortality.
Assuntos


Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: COVID-19 Tipo de estudo: Estudo observacional / Fatores de risco Limite: Feminino / Humanos / Masculino País/Região como assunto: América do Sul / Peru Idioma: Espanhol Revista: Rev. méd. Chile Assunto da revista: Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: Peru Instituição/País de afiliação: Hospital Santa Rosa Piura/PE / Sanidad del Grupo 7-FAP/PE / Universidad Norbert Wiener/PE / Universidad San Ignacio de Loyola/PE

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: COVID-19 Tipo de estudo: Estudo observacional / Fatores de risco Limite: Feminino / Humanos / Masculino País/Região como assunto: América do Sul / Peru Idioma: Espanhol Revista: Rev. méd. Chile Assunto da revista: Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: Peru Instituição/País de afiliação: Hospital Santa Rosa Piura/PE / Sanidad del Grupo 7-FAP/PE / Universidad Norbert Wiener/PE / Universidad San Ignacio de Loyola/PE