SARS-Cov-2 infection and severe proximal myopathy secondary to dermatomyositis and overlap systemic sclerosis: A Case Report from Zambia
Medical Journal of Zambia
;
49(1): 82-90, 2022. figures, tables
Artigo
em Inglês
| AIM
| ID: biblio-1390652
ABSTRACT
Background:
Myositis has been reported to be associated or triggered by viruses. Genetic and environmental factors are documented risk for myopathies. Viruses have also been shown to modify the clinical course of auto-immune diseases. We therefore report a case of SARS-Cov-2 infection in a 26-year-old female black Zambian patient with proximal myopathy. Case Presentation We present the case of a 26-yearold chemical factory worker with severe acute respiratory distress syndrome corona virus 2 (SARS-cov-2) infection and proximal myopathy. She presented to a local private hospital with fever, weakness and flu-like symptoms after being exposed to a colleague diagnosed with SARS-cov-2 infection at the time Zambia declared the July 2021 third wave of SARS-cov-2pandemic. She also reported difficulties in climbing stairs, had Raynaud's phenomenon, proximal myopathy, classic dermatomyositis features, symptoms of systemic sclerosis, raised creatine phosphokinase (CPK), and a positive nasopharyngeal PCR test for SARS-Cov-2 infection.Conclusions:
We presented, for the first time in Zambia, the case of a patient with SARS-Cov-2 infection and severe proximal myopathy secondary to newly diagnosed dermatomyositis and overlap systemic sclerosis. The myopathy appeared to have been worsened by SARS-Cov-2 viral infection.
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Esclerose
/
Dermatomiosite
/
COVID-19
/
Doenças Musculares
Idioma:
Inglês
Revista:
Medical Journal of Zambia
Ano de publicação:
2022
Tipo de documento:
Artigo
Instituição/País de afiliação:
Eden University, School of Medicine/ZM
/
Lusaka Apex Medical University, School of Medicine, Department of Medicine/ZM
/
Mum's Care Hospital/ZM
/
University of Zambia, School of Medicine, University Teaching Hospital/ZM
/
velyn Hone Colleges of Applied Arts and Commerce, School of Applied Health and Sciences, Medical Imaging Department/ZM
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