Metabolic syndrome and its components among HIV/AIDS patients on Antiretroviral Therapy and ART-Naïve Patients at the University of Calabar Teaching Hospital, Calabar, Nigeria
African Health Sciences
;
22(1): 410-417, March 2022. Tables
Artigo
em Inglês
| AIM
| ID: biblio-1400643
ABSTRACT
Background:
Although an increasing access to ART in sub-Saharan Africa has made it possible for HIV/AIDS patients to live longer, clinicians managing such patients are faced with the challenge of drug-related metabolic complications.Methods:
A cross -sectional study was carried out at the University of Calabar Teaching Hospital, Nigeria, on three groups of participants; namely HIV patients on ART, ART-naïve patients and HIV negative subjects (n =75). Demographic and anthropometric data were collected using a well-structured questionnaire while biochemical parameters were measured using colorimetric methods.Results:
The highest prevalence of MS was associated with the HIV/AIDS patients on ART (i.e. 32.0 %, and 50.3% for NCEP-ATP III and IDF criteria respectively). Patients on ART had significant increases (p< 0.05) in waist to hip ratio, FPG, serum TG and LDL-c; and a significantly higher (p< 0.05) prevalence of hypertension, diabetes, low HDL-c and hypertriglyceridemia compared to the ART-naïve patients. Low serum HDL-c was the most prevalent form of dyslipidemia in all three groups and the most prevalent component of MS in HIV patients.Conclusion:
ART increases the risk of MS and CVD. HIV/AIDS patients on ART should be advised on lifestyle modifications and undertake regular assessment of their cardiovascular risk factors
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Pacientes
/
Síndrome da Imunodeficiência Adquirida
/
HIV
/
Terapia Antirretroviral de Alta Atividade
/
Ativação Metabólica
Tipo de estudo:
Estudo observacional
/
Pesquisa qualitativa
/
Fatores de risco
País/Região como assunto:
África
Idioma:
Inglês
Revista:
African Health Sciences
Ano de publicação:
2022
Tipo de documento:
Artigo
Instituição/País de afiliação:
Akwa Ibom State Hospital Management Board, Uyo, Nigeria, Akwa Ibom State Hospital Management Board/NG
/
University of Buea , Medical Laboratory Sciences/NG
/
University of Buea, Cameroon, Medical Laboratory Sciences/NG
/
University of Calabar, Nigeria, Medical Laboratory Sciences/NG
/
University of Calabar, Nigeria, Medical Laboratory Sciences, Faculty of Allied Medical Sciences/NG
/
University of calabar, department of medical laboratory science/NG
Similares
MEDLINE
...
LILACS
LIS