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Antibiotic susceptibility patterns of bacterial isolates of patients with upper respiratory tract infections
Ullah, Kalim; Baloch, Marvi; Saleem, Fahad; Khan, Ayaz Ali; Saeed, Hamid; Islam, Muhammad.
  • Ullah, Kalim; University of Balochistan. Faculty of Pharmacy & Health Sciences. Quetta. PK
  • Baloch, Marvi; University of Balochistan. Faculty of Pharmacy & Health Sciences. Quetta. PK
  • Saleem, Fahad; University of Balochistan. Faculty of Pharmacy & Health Sciences. Quetta. PK
  • Khan, Ayaz Ali; University of Balochistan. Faculty of Pharmacy & Health Sciences. Quetta. PK
  • Saeed, Hamid; University of the Punjab. University College of Pharmacy. Lahore. PK
  • Islam, Muhammad; University of the Punjab. University College of Pharmacy. Lahore. PK
Braz. J. Pharm. Sci. (Online) ; 58: e20484, 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1403701
ABSTRACT
Abstract To evaluate the antibiotic susceptibility patterns in URTIs reporting to tertiary hospitals of Lahore. A cross-sectional study employing 259 culture sensitivity reports obtained from tertiary care hospitals of Lahore. Using SPSS, descriptive statistics were used to estimate frequencies and percentages. In URTIs, S. aureus (5%) was the frequent gram-positive isolate followed by MRSA (1.5%) and MSSA (1.5%), while P. aeruginosa (15.8%) was the prevalent gram-negative isolate followed by Klebsiella (13.1%) and E. coli (6.9%). Against P. aeruginosa, ceftazidime (7.7%), cefuroxime/ceftriaxone (4.6%), amoxicillin (4.3%) and ciprofloxacin (4.2%), were tested resistant, while imipenem (11.2%), ciprofloxacin (9.2%), amikacin (9.2%), meropenem/ levofloxacin/gentamicin (8.1%) and piptaz (6.9%) were found sensitive. Against Klebsiella, carbepenems (7.3%), amikacin (6.5%), ciprofloxacin (5.4%) and gentamicin (5%) were tested sensitive, whereas, ceftazidime (8.5%), ceftriaxone (5.8%), cefaclor (5.5%), ampicillin (4.6%), co-amoxiclave (4.2%) and ciftazidime/ciprofloxacin (3.8%) were found resistant. Overall, imipenem (35%), meropenem (30.8%) and amikacin (31.9%) were the three most sensitive antibiotics, while ceftazidime (25.4%), ceftriaxone (19.2%) and ampicillin (18.5%) were the three most resistant antibiotics. Data suggested that P.aeruginosa and Klebsiella, were the most frequent bacterial isolates in URTIs of Lahore. These isolates were resistant to ampicillin, cefuroxime and ceftazidime, but were sensitive to carbapenem and aminoglycosides
Assuntos


Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Pacientes / Infecções Respiratórias / Antibacterianos Tipo de estudo: Estudo observacional País/Região como assunto: Ásia Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2022 Tipo de documento: Artigo País de afiliação: Paquistão Instituição/País de afiliação: University of Balochistan/PK / University of the Punjab/PK

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Pacientes / Infecções Respiratórias / Antibacterianos Tipo de estudo: Estudo observacional País/Região como assunto: Ásia Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2022 Tipo de documento: Artigo País de afiliação: Paquistão Instituição/País de afiliação: University of Balochistan/PK / University of the Punjab/PK