Is Ozone therapy an adjunct treatment for SARS-CoV-2 / COVID-19 infection?
Braz. J. Pharm. Sci. (Online)
;
58: e20775, 2022. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1403724
ABSTRACT
Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highlighting the mechanisms of action, forms of application and current clinical evidence. A systematic review was conducted in electronic databases, searching the terminology Ozone "or" Ozone therapy "and" SARS-CoV-2 or COVID-19 or Coronavirus. Results:
nineteen studies were included; ten were editorials, comments, brief reports or reviews, and nine clinical studies. We found that ozone therapy could be favorable for treating patients infected with SARS-CoV-2 / COVID-19, through a direct antiviral effect, regulation of oxidative stress, immunomodulation and improvement of oxygen metabolism. Patients who were treated with ozone therapy responded favorably; therefore, ozone therapy appears to be a promising treatment for patients infected with SARS-CoV-2 / COVID-19. Its mechanism of action justifies its use as an adjuvant therapy; however, scientific evidence is based on case series and clinical trials are necessary to corroborate its effectiveness and safety.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Coronavirus
/
SARS-CoV-2
/
COVID-19
/
Ozonioterapia
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Idioma:
Inglês
Revista:
Braz. J. Pharm. Sci. (Online)
Assunto da revista:
Farmacologia
/
Teraputica
/
Toxicologia
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
Autonomous University of Yucatan/MX
/
Juarez Autonomous University of Tabasco/MX
/
Medical Center Aruku/MX
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