Prognostic value of the TyG index for in-hospital mortality in nondiabetic COVID-19 patients with myocardial injury
Rev. Assoc. Med. Bras. (1992, Impr.)
;
68(9): 1297-1302, Sept. 2022. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1406640
ABSTRACT
SUMMARY OBJECTIVE:
The purpose of this study was to explore the efficacy of the triglyceride glucose (TyG) index on in-hospital mortality in nondiabetic coronavirus disease 2019 (COVID-19) patients with myocardial injury.METHODS:
This was a retrospective study, which included 218 nondiabetic COVID-19 patients who had myocardial injury. The TyG index was derived using the following equation log [serum triglycerides (mg/dL) ×fasting blood glucose (mg/dL)/2].RESULTS:
Overall, 49 (22.4%) patients died during hospitalization. Patients who did not survive had a higher TyG index than survivors. In multivariate Cox regression analysis, it was found that the TyG index was independently associated with in-hospital death. A TyG index cutoff value greater than 4.97 was predicted in-hospital death in nondiabetic COVID-19 patients with myocardial damage, with 82% sensitivity and 66% specificity. A pairwise evaluation of receiver operating characteristic (ROC) curves demonstrated that the TyG index (AUC 0.786) had higher discriminatory performance than both triglyceride (AUC 0.738) and fasting blood glucose (AUC 0.660) in predicting in-hospital mortality among these patients.CONCLUSIONS:
The TyG index might be used to identify high-risk nondiabetic COVID-19 patients with myocardial damage.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Rev. Assoc. Med. Bras. (1992, Impr.)
Assunto da revista:
EducaÆo em Sa£de
/
GestÆo do Conhecimento para a Pesquisa em Sa£de
/
Medicina
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Doctor Nafiz Korez Sincan State Hospital/TR
/
Health Sciences University/TR
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