Leucemia mieloide crónica atípica BCR-ABL1 negativa: reporte de 2 casos / BCR-ABL1 negative chronic myeloid leukemia: report of two cases
Rev. méd. Chile
;
150(3): 397-401, mar. 2022. ilus, tab
Artigo
em Espanhol
| LILACS
| ID: biblio-1409816
ABSTRACT
BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Trombocitopenia
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Leucemia Mieloide Crônica Atípica BCR-ABL Negativa
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Universidad de Concepción/CL
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