Phenotypic Characterisation of Staphylococcus aureus Isolated from Patients in Healthcare Institutions in Zaria Metropolis, Kaduna State, Nigeria
West Afr. j. med
; 39(11): 1148-1155, 2022. tales, figures
Article
em En
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| ID: biblio-1410936
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ABSTRACT
BACKGROUND:
Staphylococcus aureus is a cosmopolitan and pathogenic microorganism associated with various diseases spectra and antimicrobial resistance of public health importance.Aim:
This study determined the phenotypic characteristics of S. aureus isolated from patients in healthcare institutions in Zaria metropolis.STUDYDESIGN:
A cross-sectional hospital-based study was carried out in 5 healthcare institutions. Four hundred and twenty clinical samples were collected and analyzed.RESULTS:
Majority of the patients (54.3%) were within the age range 2140 years and mean age of 26.04 ± 12 years. Approximately, 70% of the respondents had history of antibiotic use prior to consultation in the hospitals and wereselfprescribed, and 91.2% were outpatients. The most commonly abused antibiotics were ampicillin-cloxacillin (19.5%) and cotrimoxazole (10.0%), and the mean duration of their use was 3.5 ± 1.3 days. The detection rate for S. aureus was 10% and 5.2% for MRSA. The S. aureus isolates showed the highest frequency of resistance against ampicillin 42 (100%), followed by penicillin G 39 (92.9%) and least was to gentamicin 5 (11.9%). The frequency of resistance for the MRSA were ampicillin 22 (100%), penicillin G 21(95.5%) and least was to gentamicin 2 (9.1%). The minimum inhibitory concentrations of oxacillin were greater than 128 µg /ml.CONCLUSION:
The detection rate of S. aureus and MRSA strains are of great public health concern which requires continuous health education on rational use of antibiotics among othersPalavras-chave
Texto completo
- https://wajmed.com/ojs3.3__wajm/index.php/wajmed/article/view/297/163
- https://indexmedicus.afro.who.int/iah/fulltext/Phenotypic Characterisation of Staphylococcus aureus Isolated from Patients in Healthcare Institutions in Zaria Metropolis, Kaduna State, Nigeria.pdf
- https://fi-admin.bvsalud.org/document/view/4pae4
Texto completo:
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Índice:
AIM
Assunto principal:
Fenótipo
/
Staphylococcus aureus
Limite:
Humans
Idioma:
En
Revista:
West Afr. j. med
Ano de publicação:
2022
Tipo de documento:
Article