Assessment of salivary opiorphin in oral lichen planus
Braz. j. oral sci
;
22: e237270, Jan.-Dec. 2023. ilus
Artigo
em Inglês
| LILACS, BBO
| ID: biblio-1413378
ABSTRACT
Opiorphin is a pentapeptide, which could be isolated from human fluids and has a decreasing effect on pain. Aim:
Since lichen planus is a chronic mucocutaneous disease, which causes pain or burning feeling in the oral mucosa, this study aimed to compare salivary opiorphin levels of oral lichen planus (OLP) patients with healthy subjects.Methods:
This case-control study, was performed on 24 patients with OLP lesions and 21 healthy subjects. After collecting unstimulated saliva, opiorphin levels were compared between two groups through statistical analyses.Results:
There was not any significant difference between OLP patients and healthy subjects according to salivary opiorphin concentration (p=0.378). Also, in the OLP group, opiorphin concentration was not significantly different between males and females (p=0.601). Analytical analysis could not show any remarkable difference between various severity of OLP lesions regarding to salivary opiorphin levels (p=0.653).Conclusion:
In this study, salivary opiorphin levels was not significantly different between patients with OLP and healthy subjects; however, more studies are suggested for better assessment of salivary opiorphin levels in various types of OLP lesions and its correlation with pain severityAssuntos
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Oligopeptídeos
/
Dor
/
Saliva
/
Líquen Plano Bucal
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Braz. j. oral sci
Assunto da revista:
Odontologia
Ano de publicação:
2023
Tipo de documento:
Artigo
País de afiliação:
Irã
Instituição/País de afiliação:
Mashhad University of Medical Sciences/IR
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