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Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
Huy, Roan Ngoc Anh; Govindan, Ramu; Sivaramakumar, Navanita; Raman, Rajesh; Jayaraman, Saravanan; Basavan, Duraiswamy; Palanisamy, Dhanabal S.
  • Huy, Roan Ngoc Anh; JSS Academy of Higher Education & Research. JSS College of Pharmacy. Department of Pharmacognosy. Ooty, Nilgiris. IN
  • Govindan, Ramu; JSS Academy of Higher Education & Research. JSS College of Pharmacy. Department of Pharmacognosy. Ooty, Nilgiris. IN
  • Sivaramakumar, Navanita; JSS Academy of Higher Education & Research. JSS College of Pharmacy. Department of Pharmacognosy. Ooty, Nilgiris. IN
  • Raman, Rajesh; JSS Academy of Higher Education and Research. JSS College of Pharmacy. Department of Pharmaceutical Biotechnology. Ooty, Nilgiris. IN
  • Jayaraman, Saravanan; JSS Academy of Higher Education and Research. JSS College of Pharmacy. Department of Pharmacology. Ooty, Nilgiris. IN
  • Basavan, Duraiswamy; JSS Academy of Higher Education & Research. JSS College of Pharmacy. Department of Pharmacognosy. Ooty, Nilgiris. IN
  • Palanisamy, Dhanabal S; JSS Academy of Higher Education & Research. JSS College of Pharmacy. Department of Pharmacognosy. Ooty, Nilgiris. IN
Braz. J. Pharm. Sci. (Online) ; 58: e20582, 2022. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1420384
ABSTRACT
Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.


Texto completo: DisponíveL Índice: LILACS (Américas) Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2022 Tipo de documento: Artigo / Documento de projeto País de afiliação: Índia Instituição/País de afiliação: JSS Academy of Higher Education & Research/IN / JSS Academy of Higher Education and Research/IN

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Texto completo: DisponíveL Índice: LILACS (Américas) Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2022 Tipo de documento: Artigo / Documento de projeto País de afiliação: Índia Instituição/País de afiliação: JSS Academy of Higher Education & Research/IN / JSS Academy of Higher Education and Research/IN