Maternal prepregnancy obesity and gestational diabetes influence on adverse perinatal outcomes
Arch. endocrinol. metab. (Online)
;
67(4): e000605, Mar.-Apr. 2023. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1439221
ABSTRACT
ABSTRACT Objective:
Evaluate the influence of isolated and associated prepregnancy obesity and gestational diabetes mellitus (GDM) on adverse perinatal outcomes. Materials andmethods:
Cross-sectional observational study with women who delivered at a Brazilian Maternity Hospital, between August and December 2020. Data were collected by interview with application form, and medical records. Sample was stratified by body mass index (BMI) and GDM screening in four groups no obesity (BMI < 30 kg/m2) no GDM - reference; isolated GDM; isolated obesity (BMI ≥ 30 kg/m2); and obesity with GDM. Preeclampsia (PE), cesarean section (CS), large-for-gestational-age (LGA) newborn and admission to neonatal intensive care unit (NICU) were analyzed by odds ratio (OR) adjusted for confounding factors, adopting 95% confidence interval (CI) and P < 0.05 statistically significant.Results:
From 1,618 participants, isolated obesity group (233/14.40%) had high chance of PE (OR = 2.16; CI 1.364-3.426; P = 0.001), isolated GDM group (190/11.74%) had high chance of CS (OR = 1.736; CI 1.136-2.652; P = 0.011) and NICU admission (OR = 2.32; CI 1.265-4.261; P = 0.007), and obesity with GDM group (121/7.48%) had high chance of PE (OR = 1.93; CI 1.074-3.484; P = 0.028), CS (OR = 1.925; CI 1.124-3.298; P = 0.017) and LGA newborn (OR = 1.81; CI 1.027-3.204; P = 0.040), compared with reference (1,074/66.38%).Conclusion:
Obesity and GDM enhances the chance of different negative outcomes, worsening this prognosis when associated.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Arch. endocrinol. metab. (Online)
Assunto da revista:
Endocrinologia
/
Metabolismo
Ano de publicação:
2023
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade da Região de Joinville/BR
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