Prevalence of Donor-Associated Infections in Lung Transplant Recipients
Rev. am. med. respir
;
22(1): 41-50, mar. 2022. graf
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1441103
ABSTRACT
Abstract The infectious complication is the most common condition after a transplantation. There is a limited description regarding the preva lence of donor-associated infections (DAIs) in lung transplant (LTx) recipients. There are reports of DAIs in LTx recipients of 7.6%, with documented prophylactic failure of 5.6%. Objective:
to estimate the frequency of donor-associated infections after lung transplantation and their outcome in terms of overall survival (OS).Methodology:
an observational, descriptive study, carried out in a transplant center in Argentina between January 2018 and June 2020. The study included all the patients who underwent a transplantation within such period and those with defined/proven DAIs.Results:
during the aforementioned period, 65 LTx were performed in 64 individuals (one patient underwent transplantation and subsequent retransplantation in the same study period). The median age was 39 (12-72) years. Cystic fibrosis was the main reason for transplantation (26.2%) In 61/65 cases (94%), germs were isolated from biological samples collected from the donor 78.6% in the preservation liquid, 73.7% in donor secretions, 21.3% surgical samples, and 4.9% blood cultures. Donor-associated infections were identified in 2/61 cases (prevalence of 3.1%; 95% CI 0.4-10.7%), with a median posttransplant OS of 12 months, and an OS of 98.4% (95% CI 91.7-99.9%).Conclusion:
the prevalence of DAIs in LTx recipients in the present series was 3.1% higher than the figures documented for solid organ transplants in general (< 1%), but lower than the numbers found in the few published reports (7.6%).
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Estudo de prevalência
/
Fatores de risco
Idioma:
Inglês
Revista:
Rev. am. med. respir
Assunto da revista:
Medicina
/
Pneumologia
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Argentina
Instituição/País de afiliação:
Hospital Universitario Fundación Favaloro/AR
Similares
MEDLINE
...
LILACS
LIS