Stem cell therapy in stargardt disease: a systematic review
Journal of Ophthalmic and Vision Research
;
18(3): 318-327, 23/07/2023.
Artigo
em Inglês
| AIM
| ID: biblio-1443312
ABSTRACT
This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved. These studies utilized different kinds of stem cells, including human or mouse embryonic stem cells, mesenchymal stem cells, bone marrow mononuclear fraction, and autologous bone marrow-derived stem cells. In addition, different injection techniques including subretinal, intravitreal, and suprachoroidal space injections have been evaluated. Although stem cell therapy holds promise in improving visual function in patients with Stargardt disease, further investigation is needed to determine the long-term benefits, safety, and efficacy in determining the best delivery method and selecting the most appropriate stem cell type.
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Doença de Stargardt
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Idioma:
Inglês
Revista:
Journal of Ophthalmic and Vision Research
Ano de publicação:
2023
Tipo de documento:
Artigo
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