Value of dynamic subtraction MRI in assessing HCC response to image-guided loco-regional therapy
Afr. J. Gastroenterol. Hepatol
;
6(1): 1-23, 2023. figures, tables
Artigo
em Inglês
| AIM
| ID: biblio-1512693
ABSTRACT
Background:
Hepatocellular carcinoma (HCC) is considered one of the foremost cancers worldwide. Although the hepatic resection of HCC has a high existence in the clinical scenarios, locoregional management is preferred owing to the preservation of hepatic parenchyma with lower morbidity and mortality. Dynamic contrast-enhanced MR with subtraction imaging improves the evaluation of managed HCC with easy detection of residual or recurrent viable lesions. Patients andmethods:
This study was designed in a retrospective pattern from December 2020 to December 2022. Forty patients were referred to our radiology department with solitary HCC, underwent therapeutic intervention, then underwent follow-up by dynamic MRI study.Results:
Forty patients with solitary HCC were conducted during our study; all underwent locoregional therapy with follow-up by dynamic MRI with subtraction technique one month later. The subtraction image has a sensitivity of 100%, specificity of 100%, PPV of 100%, NPV of 100%, and 100% accuracy, compared to 90.91%, 77.78%, 83.33%, 87.5%, and 85% for conventional dynamic images, 45.45%, 100%, 100%, 60% and 70% for diffusion-weighted images. Analysis of those results exhibited a considerable additive value of the subtraction technique to the dynamic MRI to detect the response of HCC after management.Conclusions:
Subtraction MRI is a pivotal tool to assess the interventional treatment of HCC, particularly in lesions having pre-contrast high signal intensity with distinguished radiologists' confidenceAssuntos
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Imageamento por Ressonância Magnética
/
Sensibilidade e Especificidade
/
Neoplasias Hepáticas
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Afr. J. Gastroenterol. Hepatol
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
Internal Medicine Department, Alexandria University/EG
/
Radiology Department, National Liver Institute, Menoufia University/EG
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